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Which is the best vaccine?

 


The world has started vaccinating. When it comes to getting vaccinated against Corona, which one would you prefer? Which vaccine is the best or with the least side effects? When you get an option to choose either covishield or covaxin, which one has minimum side effects? 

Common side effects due to vaccinations

It is very common to feel pain or get swollen in the vaccinated area. Systematic side effects include headaches, fever, fatigue. These are the common side effects people suffer from, also there can be some rare side effects. Not all those who are vaccinated get these side effects. But side effects are proportionated to 10-30% of the people who are vaccinated. Here a question may arise, if I have a pre-medical condition then am I at a higher risk of getting side effects? And the obvious answer is "it is idiosyncratic." There is no way of predicting whom it is going to affect.

Types of vaccine

Vaccines are classified into 3 categories based on their nature. Firstly, Inactivated vaccine, A virus is inactivated in the lab using chemicals. It means that these types of vaccines are less harmful generally. Then these inactivated viruses are used in vaccine production. India's Covaxin comes under this category. Secondly, the Viral vector vaccine, In these types of vaccines a family of viruses is taken and the genetic code of the virus is replaced with the genetic code of the SARS-COV2 virus. This modified virus is injected through the vaccine, this is known as the Viral vector vaccine. A vector is a medium that carries the parasites, similarly here the family viruses act as a vector. Lastly comes the third category, the mRNA vaccine. mRNA is taken from the spike proteins and used to create the vaccines. Like humans have DNA(double-stranded) viruses have RNA(single-stranded). mRNA(messenger-RNA) is obtained from the spike protein and the vaccines are created. 

What causes a virus to change to a new variant?

When a virus is spreading widely in the country and causing many infections, the possibility of the virus mutation raises. The more chances a virus has to infect, the more it replicates – and the more opportunities it has to mutate. Most viral mutations have little to no impact on the virus’s ability to cause infections and disease. But depending on where the changes are located in the virus’s genetic material, These genetic modifications may affect the exact characteristics of the virus. 

Effective against new strains

Many new strains have emerged in India, The UK, South Africa will all the vaccines protect us from these evolved viruses? Till now the UK strain is very transmissible but all the vaccines are doing a great job. Also, vaccines are expected to provide some protection against new variants because these vaccines help our body in creating a wide range of antibodies and cells. Therefore, mutations in the virus won't make the vaccine completely ineffective. 

Vaccinated vs recovered person

Single covid-19 vaccine dose boosts protection in previously infected- The Hindu

A person who has recovered from Covid has better immunity than a vaccinated person? In my opinion, solid protection happens when you are recovered from covid and got vaccinated. Now you are given a first dose of the vaccine, then there is a boost in antibodies. Researchers found that people who had previously had mild or asymptomatic infection had significantly enhanced protection against the Kent and South Africa variants, after a single dose of the mRNA vaccine.


I hope this article helps you. Stay safe, stay healthy. Get vaccinated.

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